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Title:
SOMATOSTATIN VECTOR
Document Type and Number:
Japanese Patent JP2010265271
Kind Code:
A
Abstract:

To provide a targeted cytotoxic compound and a method related to its therapeutic use for the treatment of neoplasia and other conditions.

This targeted cytotoxic compound is provided by including a cytotoxic part bonded with a targeted part such as a ligand of a biological receptor. The cytotoxic part is anthracycline, camptothecine, paclitaxel, doxorubicin or their derivatives, and the targeted part is somatostatin, bombesin, LHRH, their analogues, the ligand or the derivatives of the analogues.

COPYRIGHT: (C)2011,JPO&INPIT


Inventors:
DONG ZHENG XIN
SHEN YEELANA
COMSTOCK JEANNE MARY
KIM SUN H
Application Number:
JP2010133732A
Publication Date:
November 25, 2010
Filing Date:
June 11, 2010
Export Citation:
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Assignee:
IPSEN PHARMA SAS
International Classes:
C07K7/06; A61K31/337; A61K31/351; A61K31/475; A61K31/704; A61K38/01; A61K38/02; A61K38/03; A61K38/04; A61K38/05; A61K38/06; A61K38/07; A61K38/08; A61K38/09; A61K38/10; A61K38/12; A61K38/16; A61K38/22; A61K38/24; A61K38/31; A61K47/48; A61P9/10; A61P11/00; A61P13/08; A61P35/00; C07K2/00; C07K7/00; C07K7/02; C07K7/08; C07K7/23; C07K7/50; C07K7/64; C07K11/00; C07K14/00; C07K14/655; C07K14/665; C07K19/00; A61K
Domestic Patent References:
JP2002047298A2002-02-12
JP4578470B22010-11-10
Foreign References:
WO2003028527A22003-04-10
WO2002100888A12002-12-19
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri