Title:
特定の置換型アミド、その製造方法及び使用方法
Document Type and Number:
Japanese Patent JP5563301
Kind Code:
B2
Abstract:
At least one chemical entity chosen from compounds of Formula 1 and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, and mixtures thereof is described herein. Pharmaceutical compositions comprising at least one chemical entity of the invention, together with at least one pharmaceutically acceptable vehicle chosen from carriers adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described.
Inventors:
Brom Glen, Peter A.
Lee, Son H.
Mitchell, Scott A.
Shu, Chiang Chun
Schmid, Aaron See.
Lee, Son H.
Mitchell, Scott A.
Shu, Chiang Chun
Schmid, Aaron See.
Application Number:
JP2009527626A
Publication Date:
July 30, 2014
Filing Date:
September 11, 2007
Export Citation:
Assignee:
Jiried Connecticut, Incorporated
International Classes:
C07D401/12; A61K9/06; A61K9/08; A61K9/10; A61K9/12; A61K9/20; A61K9/48; A61K9/70; A61K31/4439; A61K31/444; A61K31/4545; A61K31/497; A61K31/501; A61K31/506; A61K31/5377; A61K45/00; A61P11/02; A61P11/06; A61P21/04; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; C07D401/14; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D495/04; C07D498/04; C07D513/04
Domestic Patent References:
| JP2005255675A |
Foreign References:
| WO2006065946A1 | ||||
| WO2000043373A2 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Tatsunori Ikeda
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Tatsunori Ikeda