Title:
SPIRO COMPOUND
Document Type and Number:
Japanese Patent JP2002173485
Kind Code:
A
Abstract:
To provide a new spiro compound useful as a prophylactic and therapeutic agent for central nervous system diseases based on nociceptin receptor- binding action.
This spiro compound is represented by the general formula (I) [wherein ring A1 and ring A2 are each an optionally substituted benzene ring; E is a divalent chain hydrocarbon group which may be substituted; X is CO or the like; R1 is an optionally substituted hydrocarbon group or the like, or alternatively R1 may be bonded to a ring-constituting carbon atom of ring A2 to form a fused ring; and the symbol ... represents a single or double bond] or its salt.
Inventors:
ARAI TOSHIMITSU
NISHIKIMI YUJI
IMAMURA SHINICHI
KAMIYAMA KEIJI
KOBAYASHI MAKOTO
NISHIKIMI YUJI
IMAMURA SHINICHI
KAMIYAMA KEIJI
KOBAYASHI MAKOTO
Application Number:
JP2001291794A
Publication Date:
June 21, 2002
Filing Date:
September 25, 2001
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D221/20; A61K31/395; A61K31/438; A61K31/454; A61K31/4545; A61K31/4709; A61K31/496; A61K31/5377; A61K31/538; A61K31/5415; A61K31/55; A61P1/04; A61P3/04; A61P9/02; A61P13/02; A61P25/00; A61P25/04; A61P29/00; A61P43/00; C07D401/06; C07D401/12; C07D401/14; C07D405/12; C07D409/14; C07D413/06; C07D417/06; (IPC1-7): C07D221/20; A61K31/395; A61K31/438; A61K31/454; A61K31/4545; A61K31/4709; A61K31/496; A61K31/5377; A61K31/538; A61K31/5415; A61K31/55; A61P1/04; A61P3/04; A61P9/02; A61P13/02; A61P25/00; A61P25/04; A61P29/00; A61P43/00; C07D401/06; C07D401/12; C07D401/14; C07D405/12; C07D409/14; C07D413/06; C07D417/06
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)
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