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Title:
スピロ-ラクタムNMDA受容体修飾因子およびその使用
Document Type and Number:
Japanese Patent JP7036792
Kind Code:
B2
Abstract:
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders. Orally delivered formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.

Inventors:
Khan, M, Amin
Application Number:
JP2019505239A
Publication Date:
March 15, 2022
Filing Date:
August 01, 2017
Export Citation:
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Assignee:
Aptinix Incorporated
International Classes:
C07D205/12; A61K31/337; A61P25/18; A61P25/22; A61P25/24; A61P25/28
Foreign References:
US3360503
CA2058223A1
Other References:
Organic & Biomolecular Chemistry,2012年,Vol.10, No.24,pp.4752-4758
Tetrahedron Letters,1990年,Vol.31, No.28,pp.3999-4002
REGISTRY(STN)[online],2016年04月05日,[検索日 2021.05.24], CAS登録番号 1886984-68-4
REGISTRY(STN)[online],2003年03月28日,[検索日 2021.05.24], CAS登録番号 500871-61-4
REGISTRY(STN)[online],2016年03月09日,[検索日 2021.05.24], CAS登録番号 1882390-42-2 など
Attorney, Agent or Firm:
Shinki Global IP Patent Corporation