Title:
SPIRO*CYCLOHEXANE1*1**3*H**ISOBENZOFURAN* COMPOUND AND ITS MANUFACTURE
Document Type and Number:
Japanese Patent JPS5645469
Kind Code:
A
Abstract:
The present invention relates to novel spiro [cyclohexane-1,1 min (3 min H)- isobenzofuran]s of the formula …… wherein R1 is hydrogen; R2 is NR5R6 wherein R5 is hydrogen, loweralkyl; …… R6 is hydrogen or loweralkyl; R3 is hydrogen, loweralkyl or cycloalkyl having 3 to 7 carbon atoms, inclusive …… wherein X is hydrogen, halogen or loweralkyl; R is hydrogen, loweralkyl or hydroxy; R3 and R4 taken together with the carbon atom to which they are attached form a carbonyl group; the geometrical isomers and optical antipodes thereof and the pharmaceutically acceptable salts thereof wherein R5 is not the …… group, which compounds exhibit antidepressant, tranquilizer, analgesic and anticonvulsant activity.
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Inventors:
ROORENSU REO MAACHIN
MANFURETSUTO BUORUMU
MANFURETSUTO BUORUMU
Application Number:
JP12297280A
Publication Date:
April 25, 1981
Filing Date:
September 06, 1980
Export Citation:
Assignee:
HOECHST ROUSSEL PHARMA
International Classes:
A61K31/34; A61P25/04; A61P25/20; A61P25/24; A61P25/26; C07D263/14; C07D307/94; C07D493/10; (IPC1-7): A61K31/34; C07D307/94