Title:
スクアリン酸誘導体
Document Type and Number:
Japanese Patent JP2008526790
Kind Code:
A
Abstract:
Novel squaric acid compounds of the formula (I), in which R, R1, R1', R2 and X have the meanings indicated in Claim ( 1 ), are SGK inhibitors and can be used for the treatment of SGK-induced diseases and complaints, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in fibroses and inflammatory processes of any type.
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Inventors:
Medellsky, Werner
Gerikke, rolf
Dolsh Dieter
Klein, Marx
Bayer, Norbert
Lange, Florian
Gerikke, rolf
Dolsh Dieter
Klein, Marx
Bayer, Norbert
Lange, Florian
Application Number:
JP2007549807A
Publication Date:
July 24, 2008
Filing Date:
December 09, 2005
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07C225/22; A61K31/137; A61P1/04; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P7/04; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P17/00; A61P19/02; A61P25/18; A61P25/28; A61P27/06; A61P27/12; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P43/00; C07C221/00; C07C227/08; C07C229/60; C07C303/40; C07C311/43
Domestic Patent References:
JPS5328642A | 1978-03-17 | |||
JP2009502820A | 2009-01-29 | |||
JP2008534633A | 2008-08-28 | |||
JP2004529911A | 2004-09-30 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Youichi Inoue
Noriki Mitsuhashi
Takakawara Yoshiko
Youichi Inoue
Noriki Mitsuhashi
Takakawara Yoshiko