安定な炭酸水素イオン含有薬液 - National University Corporation Chiba University

Title:

安定な炭酸水素イオン含有薬液

Document Type and Number:

Japanese Patent JP5329420

Kind Code:

B2

Abstract:

The invention relates to a stable bicarbonate ion-containing drug solution, particularly a bicarbonate-containing drug solution for dialysis in which the stability has been improved by the presence of a phosphate ion. Further, the invention relates to a drug solution for acute blood purification, particularly a dialysate and a substitution liquid for acute blood purification to be mixed before use containing the drug solution. Still further, the invention relates to a dialysate and a substitution liquid for acute blood purification to be mixed before use in which the formation of insoluble fine particles or precipitates is prevented for a long time after mixing and with which hypokalemeia and hypophosphatemia are not caused.

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Inventors:

Oda Adult
Tomohito Sadahiro
Nakamura Masataka
Shuichi Tanaka
Tokuoka Shogo
Yuya Otani

Application Number:

JP2009536137A

Publication Date:

October 30, 2013

Filing Date:

October 06, 2008

Export Citation:

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Assignee:

National University Corporation Chiba University
FUSO PHARMACEUTICAL INDUSTRIES,LTD.

International Classes:

A61K33/42; A61K31/7004; A61K33/06; A61K33/10; A61K33/14; A61M1/14; A61M1/28; A61P7/08

Domestic Patent References:

JPS58501109A	1983-07-14
JP2003104869A	2003-04-09
JPS58501109A	1983-07-14
JP2003104869A	2003-04-09

Other References:

JPN6008054282; Ｈ　Ｋａｔａｙａｍａ　ｅｔ　ａｌ．: 'Ｈｉｇｈ　ｆｌｏｗ　ＣＨＤＦ，　Ｈｉｇｈ　ｖｏｌｕｍｅ　ＣＨＦ' 救急・集中治療Ｖｏｌ．１８，　Ｎｏ．１-２, 2006, ｐｐ．２２４-２２８
JPN6008054284; Ｈａｓｔｉｎｇｓ，　Ａ．　ＢＡＩＲＤ　ｅｔ　ａｌ．: 'Ｓｔｕｄｉｅｓ　ｏｆ　ｔｈｅ　ｓｏｌｕｂｉｌｉｔｙ　ｏｆ　ｃａｌｃｉｕｍ　ｓａｌｔｓ．　Ｉ．　Ｔｈｅ　ｓｏｌｕｂｉｌｉｔｙ　ｏｆ　ｃａｌｃｉｕｍ　ｃａｒｂｏｎａｔｅ　ｉｎ　ｓａｌｔ　ｓｏｌｕｔｉｏｎｓ' Ｊ　Ｂｉｏｌ　ＣｈｅｍＶｏｌ．７１，　Ｎｏ．３, 1927, ｐｐ．７２３-７８１
JPN6008054282; Ｈ　Ｋａｔａｙａｍａ　ｅｔ　ａｌ．: 'Ｈｉｇｈ　ｆｌｏｗ　ＣＨＤＦ，　Ｈｉｇｈ　ｖｏｌｕｍｅ　ＣＨＦ' 救急・集中治療Ｖｏｌ．１８，　Ｎｏ．１-２, 2006, ｐｐ．２２４-２２８
JPN6008054284; Ｈａｓｔｉｎｇｓ，　Ａ．　ＢＡＩＲＤ　ｅｔ　ａｌ．: 'Ｓｔｕｄｉｅｓ　ｏｆ　ｔｈｅ　ｓｏｌｕｂｉｌｉｔｙ　ｏｆ　ｃａｌｃｉｕｍ　ｓａｌｔｓ．　Ｉ．　Ｔｈｅ　ｓｏｌｕｂｉｌｉｔｙ　ｏｆ　ｃａｌｃｉｕｍ　ｃａｒｂｏｎａｔｅ　ｉｎ　ｓａｌｔ　ｓｏｌｕｔｉｏｎｓ' Ｊ　Ｂｉｏｌ　ＣｈｅｍＶｏｌ．７１，　Ｎｏ．３, 1927, ｐｐ．７２３-７８１

Attorney, Agent or Firm:

Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Michiko Matsutani
Sakurai Yoko
Masayuki Nakagawa
Satoshi Hashimoto
Nishino Mitsuru
Yasushi Ochiai
Mizuhara Masahiro

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