Title:
STATIN-ENCAPSULATED NANOPARTICLE PREPARATION, DENTAL PULP-DERIVED STEM CELLS CONTAINING THE SAME, AND CELL PREPARATION CONTAINING THE SAME
Document Type and Number:
Japanese Patent JP2019196342
Kind Code:
A
Abstract:
To enable the therapeutic effect on diseases to be improved by improving the functions of stem cells used as a cell preparation.SOLUTION: The present invention is a statin-encapsulated nanoparticle preparation for enhancing the function of dental pulp-derived stem cells, which comprises statin encapsulated nanoparticles in which statin is encapsulated in a nanoparticle comprising a bioabsorbable polymer.SELECTED DRAWING: None
Inventors:
II MASAAKI
HAMAZONO TOSHIRO
HAMAZONO TOSHIRO
Application Number:
JP2018091722A
Publication Date:
November 14, 2019
Filing Date:
May 10, 2018
Export Citation:
Assignee:
EDUCATIONAL FOUND OF OSAKA MEDICAL & PHARMACEUTICAL UNIV
CELL TECHONOLOGY CO LTD
CELL TECHONOLOGY CO LTD
International Classes:
A61K9/51; A61K31/366; A61K35/28; A61K47/34; A61P9/00; A61P25/00; A61P29/00; A61P43/00
Foreign References:
| WO2017191808A1 | 2017-11-09 |
Other References:
LIN, H.P. ET AL.: "Controlled release of lovastatin from poly(lactic-co-glycolic acid) nanoparticles for direct pulp ca", INTERNATIONAL JOURNAL OF NANOMEDICINE, vol. 12, JPN6019020526, 31 July 2017 (2017-07-31), pages 5473 - 5485, XP055650781, ISSN: 0004740797, DOI: 10.2147/IJN.S138410
Attorney, Agent or Firm:
Takashi Matsuzaki
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