Title:
STAUROSPORINE DERIVATIVE AND ANTIULCER EFFECT ENHANCER CONTAINING THE SAME DERIVATIVE
Document Type and Number:
Japanese Patent JPH05247055
Kind Code:
A
Abstract:
PURPOSE: To provide the subject new compound useful as an antiulcer effect enhancer.
CONSTITUTION: A compound of formula I (X is O or H2; RCO is an aliphatic acyl except acetyl, benzoyl or an alkoxycarbonyl, provided that RCO is neither t-butoxycarbonyl nor benzoyl in the case of X= H2), e.g. N-carbomethoxy-7- oxostaurosporine. The compound of formula I can be obtained by reacting staurosporine of formula II with an alkoxycarbonylation agent of formula X-CO- OR' (R' is an 1 to 4C alkyl or benzyl; X is a halogen).
Inventors:
MIYAMOTO KENICHI
KOYAMA MASAO
HARIMAYA KENZOU
NAGAOKA KOZO
KOYAMA MASAO
HARIMAYA KENZOU
NAGAOKA KOZO
Application Number:
JP4518192A
Publication Date:
September 24, 1993
Filing Date:
March 03, 1992
Export Citation:
Assignee:
MEIJI SEIKA KAISHA
International Classes:
A61K31/55; A61P35/00; C07D498/22; (IPC1-7): C07D498/22; A61K31/55