Title:
立体選択的開環反応
Document Type and Number:
Japanese Patent JP4768638
Kind Code:
B2
Abstract:
The present invention relates a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic chiral catalyst to produce a steroisomerically or regioselectively enriched product.
Inventors:
Eritsk N. Jakobsen
The Ames El Leighton
Louis E Martinez
The Ames El Leighton
Louis E Martinez
Application Number:
JP2007000183A
Publication Date:
September 07, 2011
Filing Date:
January 04, 2007
Export Citation:
Assignee:
President and Fellows of Harvard College
International Classes:
C07C213/02; B01J31/22; C07B53/00; C07B57/00; C07B61/00; C07C215/08; C07C247/02; C07C247/14; C07C251/24; C07D207/12; C07D317/36; C07F7/08; C07F7/10; C07F7/18
Domestic Patent References:
| JP5202022A | ||||
| JP6065159A |
Other References:
NUGENT, W. A.,Chiral Lewis Acid Catalysis. Enantioselective Addition of Azide to Meso Epoxides,J. Am. Chem. Soc.,1992年,114(7),p.2768-2769
BONHOTE P. and SCHEFFOLD, R.,137. Asymmetric Catalysis by Vitamin B12. The Mechanism of the Cob(I)alamin-Catalyzed Isomerization of 1,2-Epoxycyclopentane to (R)-Cyclopent-2-enol,Helvetica Chimica Acta,1991年,74,p.1425-1444
LARROW J. F. et al.,J. Org. Chem.,1994年,59(7),p.1939-1942
HAYASHI M. et al.,J. Chem. Soc., Chem. Commun.,1994年,p.2699-2700
YAMASHITA H. and MUKAIYAMA T.,Chemistry Letters,1985年,p.1643-1646
YAMASHITA H.,Bull. Chem. Soc. Jpn.,1988年,61(4),p.1213-1220
BONHOTE P. and SCHEFFOLD, R.,137. Asymmetric Catalysis by Vitamin B12. The Mechanism of the Cob(I)alamin-Catalyzed Isomerization of 1,2-Epoxycyclopentane to (R)-Cyclopent-2-enol,Helvetica Chimica Acta,1991年,74,p.1425-1444
LARROW J. F. et al.,J. Org. Chem.,1994年,59(7),p.1939-1942
HAYASHI M. et al.,J. Chem. Soc., Chem. Commun.,1994年,p.2699-2700
YAMASHITA H. and MUKAIYAMA T.,Chemistry Letters,1985年,p.1643-1646
YAMASHITA H.,Bull. Chem. Soc. Jpn.,1988年,61(4),p.1213-1220
Attorney, Agent or Firm:
Yanagita Seiji
Go Sakuma
Go Sakuma