STEREOSPECIFIC MANUFACTURE OF AZETIDINONES - CONSIGLIO NAZIONALE RICERCHE

Title:

STEREOSPECIFIC MANUFACTURE OF AZETIDINONES

Document Type and Number:

Japanese Patent JPS6118759

Kind Code:

A

Abstract:

Chiral azetidinones II (R1 optionally substituted phenyl, R2 = C1-C4 alkyl or aryl, R3 = H or an N-protecting group) are prepared by reacting compound III (R4 = carboxy protecting group) with an organometallic derivative and treating the resultant dianion with a compound IV. The azetidinones II are stereospecifically prepared by the above process and may be converted to azetidinones VIII (R5 = hydroxy protecting group), useful in the preparation of penems.

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Inventors:

KAINERI GIANFURANKO
KONTENTO MITSUSHIERU
GIAKOMINI DARIA
PANUNCHIO MAURO
FURANSESUCHI GIOFUANII

Application Number:

JP13316685A

Publication Date:

January 27, 1986

Filing Date:

June 20, 1985

Export Citation:

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Assignee:

CONSIGLIO NAZIONALE RICERCHE
ERBA CARLO SPA

International Classes:

C07D205/08; C07D477/00; C07D487/08; C07D499/06; C07D499/88; C07D499/897; C07F7/10; C07F7/18; (IPC1-7): C07D205/08; C07D487/04; C07D499/00; C07F7/10

Attorney, Agent or Firm:

Hajime Tsukuni

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