Title:
STIMULATION OF SATIETY HORMONE RELEASE
Document Type and Number:
Japanese Patent JP2014208675
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a site specific way to enhance a natural hormonal response to nutrients entering the small intestine after gastric emptying, thereby providing therapeutic value for obesity or diabetic patients.SOLUTION: Provided is a method of stimulating the release of satiety hormone in a subject comprising applying a first electrical stimulus to a tissue in the lumen of the gastrointestinal system of the subject contemporaneously with the contracting of L-cells of the tissue with a nutrient stimulus. And also provided is a method for predicting patient response to a weight loss surgery comprising applying the first electrical stimulus to a tissue of the gastrointestinal system of the patient contemporaneously with the contracting of L-cells of the tissue with a nutrient stimulus, assessing the effect of the electrical stimulus in the patient, and correlating the effect to the patient's response to a weight loss surgery.
Inventors:
PAMELA J HORNBY
TATIANA ORT
RADHIKA KAJEKAR
PAUL R WADE
TATIANA ORT
RADHIKA KAJEKAR
PAUL R WADE
Application Number:
JP2014126236A
Publication Date:
November 06, 2014
Filing Date:
June 19, 2014
Export Citation:
Assignee:
JANSSEN BIOTECH INC
International Classes:
A61K45/00; A61K31/198; A61K31/20; A61K31/215; A61K31/718; A61K38/00; A61N1/36; A61P3/04; A61P43/00
Domestic Patent References:
| JP2007527735A | 2007-10-04 |
Attorney, Agent or Firm:
Patent business corporation Odajima patent firm
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