Title:
病気の抑制と改善のための構造上のカロチノイド類似体
Document Type and Number:
Japanese Patent JP5187700
Kind Code:
B2
Abstract:
A chemical compound having the structure
where each Y is independently O or H 2 ;
where each R is independently -alkyl-NR 2 3 , -alkyl-CO 2 - , or -amino acid-NH 3 + ;
where each R 2 is independently H, alkyl, or aryl, as well as its use in treating cardiovascular disease, a disease which produces reactive oxygen species, liver disease, disease which comprises cancerous and pre-cancerous cell(s), disease comprising increasing cannexin 43 expression or reducing C-reactive protein, gastrointestinal disease, muscoskeletal disease.
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Inventors:
Rockwood, Samuel, Fournia
Omaray, scene
Watumuru, David, Gee
Hicks, Laura, M.
Henry Jackson
Nadorsky, Geoff
Omaray, scene
Watumuru, David, Gee
Hicks, Laura, M.
Henry Jackson
Nadorsky, Geoff
Application Number:
JP2010170929A
Publication Date:
April 24, 2013
Filing Date:
July 29, 2010
Export Citation:
Assignee:
Caldax Pharmaceuticals, Inc.
International Classes:
A61K31/215; A01N27/00; A61K31/01; A61K31/015; A61K31/045; A61K31/07; A61K31/075; A61K31/12; A61K31/13; A61K31/185; A61K31/225; A61K31/255; A61K31/325; A61K31/401; A61K31/404; A61K31/4172; A61K31/535; A61K31/537; A61K31/5377; A61K31/66; A61K31/6615; A61K31/665; A61K31/70; A61K31/7024; A61K31/704; A61K31/715; A61P1/00; A61P1/04; A61P1/08; A61P1/16; A61P1/18; A61P3/00; A61P3/02; A61P3/10; A61P7/02; A61P7/04; A61P7/06; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/02; A61P13/08; A61P13/12; A61P15/08; A61P17/00; A61P17/04; A61P17/06; A61P17/16; A61P19/02; A61P19/08; A61P21/00; A61P25/00; A61P25/16; A61P25/28; A61P25/32; A61P27/12; A61P27/16; A61P31/04; A61P31/12; A61P33/00; A61P33/02; A61P33/06; A61P35/00; A61P35/04; A61P37/04; A61P37/06; A61P37/08; A61P39/02; A61P39/06; A61P41/00; A61P43/00; C07C403/24; C07D207/16; C07D233/60; C07D265/30; C07D307/58; C07F9/02; C07F9/117; C07H13/04
Domestic Patent References:
| JP2002513411A | ||||
| JP2001524463A | ||||
| JP2001114673A | ||||
| JP10327865A | ||||
| JP9084591A | ||||
| JP8337592A | ||||
| JP8073312A | ||||
| JP2005517010A | ||||
| JP2004528301A | ||||
| JP7118227A | ||||
| JP58148855A | ||||
| JP58079972A |
Foreign References:
| US5536504 | ||||
| US3354218 | ||||
| DE19950327A1 |
Attorney, Agent or Firm:
▲吉▼川 俊雄