Title:
構造タンパク質微小体及びその製造方法、ナノファイバーの製造方法、並びにタンパク質構造体の製造方法
Document Type and Number:
Japanese Patent JP7007008
Kind Code:
B2
Abstract:
Provided is a structural protein microbody that functions as a core for forming a protein nanofiber. There is provided a structural protein microbody including a structural protein, in which the structural protein microbody satisfies at least two of the following (i) to (iii): (i) a peak is present within a range of 480 to 500 nm in a fluorescence intensity measurement by thioflavin T staining; (ii) a peak is present in a region where Q is 0.15 or less in a modified Kratky plot of small angle X-ray scattering (SAXS); and (iii) the structural protein microbody is an aggregate of two or more structural protein molecules.
Inventors:
Hiroo Uekubo
Yugo Hayashi
Takeru Sato
Yugo Hayashi
Takeru Sato
Application Number:
JP2021522869A
Publication Date:
February 10, 2022
Filing Date:
May 28, 2020
Export Citation:
Assignee:
spiber corporation
International Classes:
C07K14/435; C07K1/30; C07K17/02; D01F4/02
Domestic Patent References:
| JP2013512265A |
Foreign References:
| WO2019054506A1 | ||||
| WO2014175179A1 | ||||
| US20160215103 | ||||
| WO2018034111A1 | ||||
| WO2017030197A1 |
Attorney, Agent or Firm:
Yoshiki Hasegawa
Yoshinori Shimizu
Naoki Fukushima
Yoshinori Shimizu
Naoki Fukushima