SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLE AND 3,5-DIAMINO-1,2,4-THIADIAZOLE, MANUFACTURE AND USE THEREOF

Title:

SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLE AND 3,5-DIAMINO-1,2,4-THIADIAZOLE, MANUFACTURE AND USE THEREOF

Document Type and Number:

Japanese Patent JPS5732274

Kind Code:

A

Abstract:

Compounds of the formula (I) wherein R1 is hydrogen, halogen, or alkyl, R2 is halogen or alkyl, R3 is hydrogen, acyl, or saturated or unsaturated alkyl, R4 and R5 are individually hydrogen, or alkyl, wherein all alkyl and acyl groups are branched or straight-chain and each contains 1 to 4 carbon atoms, X is oxygen, nitrogen, or sulfur, Y is oxygen or nitrogen, and -X-Y- is -O-N-, -N-O-, or -S-N-, or salts of the above, with certain exceptions. Methods of preparation of the compounds, as well as their use as anti-hypertensives are also disclosed.

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Inventors:

EERITSUHI KOONEN
BEN ARUMAA

Application Number:

JP9681181A

Publication Date:

February 20, 1982

Filing Date:

June 24, 1981

Export Citation:

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Assignee:

BEIERSDORF AG

International Classes:

A61K31/41; A61K31/4245; A61K31/433; A61P9/12; C07C335/28; C07D271/06; C07D271/07; C07D285/08; C07D309/12; (IPC1-7): A61K31/41; C07D271/06; C07D285/08

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