Title:
置換N―[(アミノイミノメチル又はアミノメチル)フェニル]プロピルアミド
Document Type and Number:
Japanese Patent JP4107687
Kind Code:
B2
Abstract:
The compounds according to the invention are substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides of formula I herein which exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More especially, they are Factor Xa inhibitors. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, methods for their preparation and their use, which are for treating a patient suffering from, or subject to, conditions which can be ameliorated by the administration of an inhibitor of Factor Xa.
Inventors:
Klein Scott Eye
Guatin Kevin Earl
Spada Alfred Pea
Pauls Heinz W
Gong Young
McGurry Daniel G
Guatin Kevin Earl
Spada Alfred Pea
Pauls Heinz W
Gong Young
McGurry Daniel G
Application Number:
JP50587099A
Publication Date:
June 25, 2008
Filing Date:
June 26, 1998
Export Citation:
Assignee:
Aventis Pharmaceuticals, Inc.
International Classes:
C07C257/18; A61K31/00; C07D249/04; A61K31/165; A61K31/166; A61K31/195; A61K31/215; A61K31/216; A61K31/24; A61K31/335; A61K31/357; A61K31/36; A61K31/381; A61K31/397; A61K31/40; A61K31/403; A61K31/4035; A61K31/404; A61K31/415; A61K31/4164; A61K31/4184; A61K31/4196; A61K31/426; A61K31/433; A61K31/437; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4436; A61K31/4439; A61K31/4545; A61K31/47; A61P7/00; A61P7/02; A61P43/00; C07C45/63; C07C205/06; C07C205/57; C07C229/28; C07C233/64; C07C251/02; C07C255/60; C07C259/18; C07D205/08; C07D207/325; C07D207/327; C07D209/08; C07D209/48; C07D213/40; C07D213/54; C07D213/55; C07D213/56; C07D213/57; C07D213/58; C07D213/70; C07D213/74; C07D213/82; C07D213/89; C07D215/04; C07D215/48; C07D231/14; C07D233/54; C07D233/56; C07D235/04; C07D235/06; C07D235/08; C07D249/06; C07D277/20; C07D277/28; C07D277/56; C07D285/08; C07D317/46; C07D317/60; C07D319/16; C07D319/18; C07D333/70; C07D401/04; C07D409/04; C07D417/04; C07D471/04; C07D521/00; C07D207/32
Domestic Patent References:
| JP2000502710A |
Foreign References:
| WO1995023609A1 | ||||
| WO1998031661A1 |
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Fumiaki Otsuka
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo