Title:
Ｔｏｌｌ様レセプターモジュレーターとしての置換ベンゾアゼピン
Document Type and Number:
Japanese Patent JP5756805
Kind Code:
B2
Abstract:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
Inventors:
Howbert, james jeffrey
Ditch, Gregory
Robert Hirschberg
Burgess, Lawrence E.
Doherty, George A.
Iary, Sea. Todd
Gronberg, Robert Dee.
Jones, Zachary
Ditch, Gregory
Robert Hirschberg
Burgess, Lawrence E.
Doherty, George A.
Iary, Sea. Todd
Gronberg, Robert Dee.
Jones, Zachary
Application Number:
JP2012525676A
Publication Date:
July 29, 2015
Filing Date:
August 18, 2010
Export Citation:
Assignee:
VentiRx Pharmaceuticals,Inc.
International Classes:
C07D223/16; A61K31/55; A61P9/00; A61P11/06; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D401/04; C07D401/12; C07D403/04; C07D403/06; C07D403/10
Domestic Patent References:
| JP2009504763A | ||||
| JP2009504764A |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita