置換ヒドロキシエチルアミン系のアスパラギン酸プロテアーゼ阻害薬

Japanese Patent JP2007528400

A

The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

WO/1994/002442	PHARMACOLOGICALLY ACTIVE alpha--BENZENEMETHANOL DERIVATIVES
WO/2005/087215	SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS
JP2005526695	How to make and use 2-hydroxy derivatives of sibutramine and its metabolites

Virgies, john
Maillard, Michael
Tucker, John
Aquino, Jose
Jagodinska, Barbara
Brogley, lewis
Tongue, jay
Bowers, Simeon
Dressen, Darren
Probst, Garry
Shah, Nilove

JP2007502959A

October 11, 2007

March 09, 2005

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Elan Pharmaceuticals, Inc.

C07C215/28; A61K31/133; A61K31/137; A61K31/165; A61K31/18; A61K31/27; A61K31/341; A61K31/351; A61K31/353; A61K31/357; A61K31/381; A61K31/382; A61K31/40; A61K31/41; A61K31/415; A61K31/4155; A61K31/4164; A61K31/4178; A61K31/4192; A61K31/4196; A61K31/42; A61K31/422; A61K31/4245; A61K31/425; A61K31/426; A61K31/427; A61K31/433; A61K31/44; A61K31/4439; A61K31/4468; A61K31/453; A61K31/47; A61K31/4709; A61K31/505; A61K31/519; A61K31/55; A61K31/5513; A61K45/00; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P43/00; C07C215/44; C07C215/50; C07C217/34; C07C217/48; C07C217/52; C07C217/54; C07C217/58; C07C225/06; C07C225/20; C07C229/16; C07C229/42; C07C229/60; C07C233/43; C07C237/20; C07C237/30; C07C271/12; C07C311/03; C07C317/28; C07C323/25; C07C323/30; C07C323/32; C07D207/14; C07D207/325; C07D211/56; C07D211/58; C07D213/74; C07D215/42; C07D223/16; C07D231/38; C07D233/16; C07D233/24; C07D233/54; C07D233/64; C07D233/88; C07D233/92; C07D239/26; C07D239/42; C07D243/14; C07D249/04; C07D249/14; C07D257/04; C07D261/14; C07D263/28; C07D271/10; C07D275/02; C07D277/20; C07D277/38; C07D285/08; C07D285/10; C07D285/12; C07D285/135; C07D307/52; C07D309/14; C07D311/68; C07D321/10; C07D333/36; C07D335/06; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D413/04; C07D413/12; C07D417/12; C07D419/12; C07D495/04; C07D207/32

JP2005511735A	2005-04-28
JP2005501015A	2005-01-13
JP2007528402A	2007-10-11

WO2003040096A2

2003-05-15

Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Norihiro Fukasawa

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