Title:
置換イミダゾールカルボン酸エステル系誘導体およびその使用
Document Type and Number:
Japanese Patent JP7215758
Kind Code:
B2
Abstract:
Disclosed is a compound as shown in formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof, or a metabolite thereof, or a deuterated derivative thereof. The compound is a structurally novel substituted imidazole formate derivative, belonging to the field of medicinal chemistry. Also disclosed are the use of the substituted imidazole formate derivative in preparing a drug with sedative, hypnotic and/or anesthetic effects, and the use of same in preparing a drug that can control the state of epilepsy. The compound has a good inhibitory effect on the central nervous system, and provides a new option for clinical screening of and/or preparation of a drug with sedative, hypnotic and/or anesthetic effects and controlling the state of epilepsy.
Inventors:
▲馬▼ ▲海▼▲軍▼
王 昌▲華▼
▲解▼ 振彪
王 昌▲華▼
▲解▼ 振彪
Application Number:
JP2020542264A
Publication Date:
January 31, 2023
Filing Date:
January 30, 2019
Export Citation:
Assignee:
Chengdu MS Pharma Company Limited
International Classes:
C07D233/90; A61K31/4164; A61K31/4178; A61P23/00; A61P25/08; A61P25/20; C07D405/12; C07D405/14; C07D409/12
Domestic Patent References:
| JP2015508415A |
Foreign References:
| CA3001431A1 | ||||
| WO2018153228A1 | ||||
| CN107445898A | ||||
| CN107382870A | ||||
| CN105663042A |
Other References:
Eur. J. Org. Chem.,2010年,4312-4320
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe
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