Title:
ヒトペルオキシゾーム増殖薬活性化受容体(PPAR)αアゴニストとしての置換フェニルプロピオン酸誘導体
Document Type and Number:
Japanese Patent JP4618845
Kind Code:
B2
Abstract:
The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor alpha (PPAR alpha ), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). It relates to substituted phenylpropanoic acid derivatives represented by a general formula (1), their pharmaceutically acceptable salts and their hydrates, and processes for preparing them.
Inventors:
Masahiro Nomura
Takahashi snow painting
Takahiro Tanase
Hiroyuki Miyaji
Masaki Tsunoda
Tomohiro Ide
Koji Murakami
Takahashi snow painting
Takahiro Tanase
Hiroyuki Miyaji
Masaki Tsunoda
Tomohiro Ide
Koji Murakami
Application Number:
JP2000157600A
Publication Date:
January 26, 2011
Filing Date:
May 29, 2000
Export Citation:
Assignee:
Kyorin Pharmaceutical Co., Ltd.
International Classes:
C07C235/60; A61K31/195; A61K31/222; A61K31/421; A61P3/06; A61P9/10; A61P43/00; C07C233/65; C07C233/66; C07C233/73; C07C321/12; C07C321/20; C07C321/28; C07C323/60; C07C323/62; C07D263/26
Domestic Patent References:
| JP2000503643A |
Foreign References:
| WO1997036579A1 |
Attorney, Agent or Firm:
Mizuno Katsufumi