Title:
がん治療に用いるためのＮＬＲＰ３モジュレーターとしての置換キナゾリン
Document Type and Number:
Japanese Patent JP7373571
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I): Formula (I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).
Inventors:
O'Malley, Daniel
Gabai, Ashbini Kumar Buoy
Norris, Derek Jay
Gon, Hoa
Jean, Yong
Jill, Patrice
Turby, Christine M
Blue Chema, Matthias
Watterson, Scott Hunter
Gabai, Ashbini Kumar Buoy
Norris, Derek Jay
Gon, Hoa
Jean, Yong
Jill, Patrice
Turby, Christine M
Blue Chema, Matthias
Watterson, Scott Hunter
Application Number:
JP2021540534A
Publication Date:
November 02, 2023
Filing Date:
January 13, 2020
Export Citation:
Assignee:
Innate Tumor Immunity, Inc.
International Classes:
C07D401/14; A61K31/517; A61K31/5365; A61K31/5377; A61K31/553; A61K39/395; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07D403/04; C07D403/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D498/04
Domestic Patent References:
| JP2008519083A | ||||
| JP2021514981A |
Foreign References:
| WO2018021977A1 | ||||
| WO2017184746A1 | ||||
| WO2017184735A1 |
Attorney, Agent or Firm:
Norito Yamao
Nagatoshi Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan
Nagatoshi Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan