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Title:
置換されたテトラサイクリン化合物。
Document Type and Number:
Japanese Patent JP2005520846
Kind Code:
A
Abstract:
The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Inventors:
Nelson Mark El.
Ohmen Kuwashi
Frechet Roger
Abatto Paul
Asefa Halleghe Wayne
Bandarage Uple
Vernier joel
Batia beena
Chen Jackson
Ismail Mohammed Wai.
Kim oak ray.
Matthews Jude
McIntyre Laura
Nirawi Mohamed
Pierson andre
Lady Luxma
Share Han Paul
Shizensky Emmanuel
Two Ligny Justin
Belma Atul Kay.
Viski Peter
Valcor Tadeushi
Amo Victor
Mechiche Rashid
Application Number:
JP2003577816A
Publication Date:
July 14, 2005
Filing Date:
March 18, 2003
Export Citation:
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Assignee:
Paratech Pharmaceuticals, Inc.
International Classes:
A61K31/65; A61P31/04; A61P43/00; C07C237/26; C07C239/18; C07C245/20; C07C251/08; C07C251/48; C07C255/25; C07C255/43; C07C255/58; C07C255/59; C07C271/28; C07C271/44; C07C275/34; C07D295/20; C07C279/18; C07C281/14; C07C309/61; C07C311/06; C07C311/19; C07C311/21; C07C317/48; C07C323/32; C07C323/60; C07D207/16; C07D211/58; C07D213/30; C07D213/61; C07D213/65; C07D213/75; C07D239/26; C07D239/30; C07D239/42; C07D261/10; C07D261/18; C07D295/108; C07D295/155; C07D295/215; C07D307/28; C07D307/52; C07D307/54; C07D307/68; C07D317/54; C07D317/60; C07D401/04; C07F7/10; (IPC1-7): C07C237/26; A61K31/65; A61P31/04; A61P43/00; C07C245/20; C07C255/59; C07C275/34; C07C279/18; C07C309/61; C07C311/06; C07D295/20; C07D307/54; C07D317/60; C07F7/10
Domestic Patent References:
JPS6485953A1989-03-30
JPH06199757A1994-07-19
JPH06199758A1994-07-19
JPS5119757A1976-02-17
JPS4969653A1974-07-05
JP2004502753A2004-01-29
JP2003509404A2003-03-11
JP2004537544A2004-12-16
JP2005506291A2005-03-03
JP2005504722A2005-02-17
JP2004530661A2004-10-07
JP2005526754A2005-09-08
JP2005514410A2005-05-19
JP2004529927A2004-09-30
Foreign References:
US3338963A1967-08-29
WO2002004407A22002-01-17
WO2001098259A12001-12-27
WO2001098236A22001-12-27
WO2001087824A22001-11-22
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi