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Title:
置換テトラサイクリン化合物
Document Type and Number:
Japanese Patent JP2008518035
Kind Code:
A
Abstract:
The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

Inventors:
Abert Paul
Asefa Hallejuway
Berniac Joel
Batia beena
Bowser Todd
Chen Jackson
Glia mark
Honeyman Laura
Ismal Mohammed Wai.
Nelson mark
Kwashio Ohmen
Pan Jin Wen
Application Number:
JP2007539189A
Publication Date:
May 29, 2008
Filing Date:
October 25, 2005
Export Citation:
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Assignee:
Paratech Pharmaceuticals, Inc.
International Classes:
C07C237/26; A61K31/65; A61P1/10; A61P1/16; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P13/00; A61P17/00; A61P19/02; A61P19/10; A61P21/04; A61P25/00; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/16; A61P29/00; A61P31/04; A61P31/12; A61P33/00; A61P33/06; A61P35/00; A61P43/00; C07C251/48; C07C255/59; C07C259/10; C07D207/335; C07D211/14; C07D211/70; C07D213/74; C07D231/12; C07D277/20; C07D277/30; C07D307/54; C07D487/04
Domestic Patent References:
JP2004502752A2004-01-29
JP2002501026A2002-01-15
Foreign References:
WO2002085303A22002-10-31
WO2004064728A22004-08-05
WO2002072031A22002-09-19
WO2003079984A22003-10-02
WO2003005971A22003-01-23
Other References:
JPN5007018979; NELSON,M.L. et al.: 'Versatile and Facile Synthesis of Diverse Semisynthetic Tetracycline Derivatives via Pd-Catalyzed Re' Journal of Organic Chemistry V68 N15, 2003, P5838-5851
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi