Title:
キナーゼ阻害剤としての置換6-フェニル-ピリド[2,3-D]ピリミジン-7-オン誘導体及びそれの使用方法
Document Type and Number:
Japanese Patent JP2010509265
Kind Code:
A
Abstract:
Compounds of formula I: wherein R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds, pharmaceutical compositions, methods of using the compounds for treatment of p38 MAP kinase-mediated diseases, and methods of using the compounds for treatment of Raf kinase-mediated diseases.
Inventors:
Gabriel, Tobias
Luk, Kin-Chun Thomas
Macintosh, Joel
Luk, Kin-Chun Thomas
Macintosh, Joel
Application Number:
JP2009535682A
Publication Date:
March 25, 2010
Filing Date:
October 31, 2007
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D471/04; A61K31/519; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P7/02; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P19/06; A61P19/10; A61P21/00; A61P25/00; A61P25/02; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P29/02; A61P31/00; A61P31/04; A61P31/12; A61P31/16; A61P31/18; A61P31/22; A61P33/06; A61P35/00; A61P35/04; A61P37/02; A61P37/06; A61P37/08; A61P39/02; A61P43/00
Domestic Patent References:
| JP2007508310A | 2007-04-05 | |||
| JP2004507540A | 2004-03-11 |
Foreign References:
| WO2005034869A2 | 2005-04-21 | |||
| WO2006082492A1 | 2006-08-10 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito