Title:
Substitution N- [1-cyano 2- (phenyl) ethyl] -2-azabicyclo [2.2. 1] heptane 3- Carboxamide which is cathepsin C inhibitor
Document Type and Number:
Japanese Patent JP6012736
Kind Code:
B2
Abstract:
The present invention is directed to compounds of Formula I: wherein R1, R2 and n are described herein. These compounds and their pharmaceutically acceptable salts thereof are inhibitors of Cathepsin C.
Inventors:
Grand Le Marc
Wust Torsten
Poutsch Alexander
Peters Stephan
Leeter Doris
Wienen Wolfgang
Wust Torsten
Poutsch Alexander
Peters Stephan
Leeter Doris
Wienen Wolfgang
Application Number:
JP2014530262A
Publication Date:
October 25, 2016
Filing Date:
September 18, 2012
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D209/52; A61K31/403; A61K31/4035; A61K31/404; A61K31/4155; A61K31/416; A61K31/4178; A61K31/4184; A61K31/4192; A61K31/423; A61K31/4245; A61K31/428; A61K31/4365; A61K31/437; A61K31/4439; A61K31/454; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/4985; A61K31/501; A61K31/506; A61K31/517; A61K31/536; A61K31/538; A61K31/551; A61K31/573; A61K45/00; A61P1/04; A61P9/10; A61P11/00; A61P29/00; A61P31/00; A61P35/00; A61P37/08; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D413/12; C07D417/12; C07D471/04; C07D487/04; C07D495/04
Domestic Patent References:
| JP2011506421A | ||||
| JP2004506612A | ||||
| JP2007510619A | ||||
| JP2006527704A | ||||
| JP2004531486A |
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori