Title:
置換イソキノリノン類およびキナゾリノン類
Document Type and Number:
Japanese Patent JP5542962
Kind Code:
B2
Abstract:
The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I) wherein Z is CH2 or N—R4 and X, R1, R2, R4, R6, R7 and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.
Inventors:
Jorg Belc Hausen
Nicolet Bushmann
Pascal Furet
Francis ジェシエ
Joanna エルゴヴィシュ * Liz Wang
Philip Holzer
Ed Hull Jacoby
Jorg Caren
舛 store Keiichi
The Carol Piso ソルドマン
Wren ハイシャ
Stefan Stutz
Nicolet Bushmann
Pascal Furet
Francis ジェシエ
Joanna エルゴヴィシュ * Liz Wang
Philip Holzer
Ed Hull Jacoby
Jorg Caren
舛 store Keiichi
The Carol Piso ソルドマン
Wren ハイシャ
Stefan Stutz
Application Number:
JP2012545293A
Publication Date:
July 09, 2014
Filing Date:
December 21, 2010
Export Citation:
Assignee:
Novartis アーゲー
International Classes:
C07D217/24; A61K31/472; A61K31/4725; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/517; A61K31/5377; A61K31/541; A61K31/551; A61K45/00; A61P35/00; A61P43/00; C07D239/82; C07D401/04; C07D401/10; C07D401/12; C07D401/14; C07D405/04; C07D405/12; C07D407/14; C07D409/12; C07D413/10; C07D413/12; C07D413/14; C07D417/12
Attorney, Agent or Firm:
Aoyama 葆
Yamada Takuji
Michiko Matsutani
Mitsutaka Iwasaki
Ochiai 康
Yamada Takuji
Michiko Matsutani
Mitsutaka Iwasaki
Ochiai 康
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