SUGAR CHAIN ARRAY

Japanese Patent JP2015099162

A

PROBLEM TO BE SOLVED: To provide a sugar chain array, to which a sugar chain is fixed, and which is useful for detection of coupling between a substance to be detected and the sugar chain, and to provide the sugar chain array to which the sugar chain is fixed, which can suppress nonspecific adsorption, coupling of the substance to be detected without coating an adsorption prevention agent.SOLUTION: It is discovered that the sugar chain array, which is developed by inventors, and to which a specific sugar chain is fixed is useful for the detection of the coupling between the substance such as a pathogen of an infection disease and its secretion to be detected. It is further discovered that, when a base material coated by a high molecular compound containing a unit having a primary amino group, a unit for holding hydrophilicity, and a unit having a hydrophobic group is used in the sugar chain array, the sugar chain can be efficiently fixed, and the nonspecific adsorption, coupling of the substance to be detected can be effectively suppressed.

NISHIMURA SHINICHIRO
MATSUSHITA TAKAHIKO
SHIMAOKA HIDEYUKI
TAKADA WATARU
IGARASHI KOTA
ABE MIDORI
ABE HIROKI
FUKUSHIMA MASAO

JP2015031370A

May 28, 2015

February 20, 2015

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UNIV HOKKAIDO
SUMITOMO BAKELITE CO

G01N33/53; G01N33/543; G01N37/00

JP2008541011A	2008-11-20
JP2006078418A	2006-03-23
JP2007326920A	2007-12-20
JP2008304427A	2008-12-18

WO2005097844A1	2005-10-20
US20060252030A1	2006-11-09

JPN7016002414; 今堀和友他監修: 生化学辞典　第１版 , 1989, 「レクチン」欄　ｐ１３７０

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