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Title:
Sulfa derivative
Document Type and Number:
Japanese Patent JP6058023
Kind Code:
B2
Abstract:
The present invention relates to sulfonamide derivatives, of formula (I): or a pharmaceutically acceptable salts thereof, wherein X, Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description, and to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. The compounds of formula (I) are Nav1.7 inhibitors useful in the treatment of a wide range of disorders, particularly pain.

Inventors:
David James Lawson
Robert Ian Stoller
Niger Alan Swain
Application Number:
JP2014546692A
Publication Date:
January 11, 2017
Filing Date:
December 06, 2012
Export Citation:
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Assignee:
Pfizer Limited
International Classes:
C07C307/06; A61K31/44; A61K45/00; A61P25/00; A61P25/04; A61P29/00; A61P43/00; C07D213/69; C07D401/12
Domestic Patent References:
JP2010522242A
JP2007501804A
JP2015523369A
JP2013532185A
JP2013531030A
Foreign References:
WO2011037192A1
Attorney, Agent or Firm:
Noh four
Junko Miyazawa
Maki Sato
Tatsuta Miyuki



 
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