Title:
スルファミド誘導体およびその製造方法と応用
Document Type and Number:
Japanese Patent JP6804540
Kind Code:
B2
Abstract:
The present invention discloses a compound shown in formula I or a stereoisomer, pharmaceutically acceptable salt, crystal form, solvate or isotopologue thereof. The compound of the present invention shows excellent inhibition activity against histone deacetylases, has remarkable inhibition effects on cancer cells, and provides a new choice of drugs used for the clinic treatment and diseases related to the abnormal activity of histone deacetylases.
More Like This:
Inventors:
Lee Jin
Lee Xueming
Tou Climbing
Mankinbashi
Zhang Wei
Lee Jingmei
Orchid swallow
Lee Lin
Lee Xueming
Tou Climbing
Mankinbashi
Zhang Wei
Lee Jingmei
Orchid swallow
Lee Lin
Application Number:
JP2018534705A
Publication Date:
December 23, 2020
Filing Date:
December 29, 2016
Export Citation:
Assignee:
HITGEN INC.
International Classes:
C07D211/96; A61K31/44; A61K31/4439; A61K31/4545; A61K31/4725; A61K31/496; A61K31/5377; A61K31/55; A61K31/551; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P37/06; C07D223/06; C07D401/12; C07D401/14
Domestic Patent References:
| JP2005525381A | ||||
| JP2008533091A | ||||
| JP2011507910A | ||||
| JP2011528013A |
Foreign References:
| US20050234033 | ||||
| WO2004013324A1 | ||||
| WO2014100438A1 |
Other References:
RN 1316494-40-2 REGISTRY 等,DATABASE REGISTRY [ONLINE] Retrieved from STN,2011年 8月12日,検索日 03 APR 2019
Attorney, Agent or Firm:
Koji Tsubouchi
Xu Ling
Xu Ling