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Title:
スルホンアミド含有複素環化合物
Document Type and Number:
Japanese Patent JP4234344
Kind Code:
B2
Abstract:
The present invention provides a sulfonamide- or sulfonylurea-containing heterocyclic compounds. Specifically, it provides a heterocyclic compound represented by the formula (I), a pharmacologically acceptable salt thereof or a hydrate of them. In the formula, A is hydrogen atom, a halogen atom, a C1-C4 alkyl or alkoxy group which may be substituted with a halogen atom, or cyano group; B is an optionally substituted aryl group or monocyclic heteroaryl group, or: (wherein, the ring Q is an aromatic ring which may have nitrogen atom; and the ring M is a ring sharing a double bond with the ring Q, which ring may have a heteroatom; and the rings Q and M may share nitrogen atom); K is a single bond; T, W, X and Y are the same as or different from each other and each is =C(D)- (wherein, D is hydrogen or a halogen atom) or nitrogen atom; U and V are the same as or different from each other and each is =C(D)-, nitrogen atom, -CH2-, oxygen atom or -CO-; Z is a single bond or -CO-NH-; and R1 is hydrogen atom, etc.

Inventors:
Haneda
Akihiko Tsuruoka
Junichi Kamada
Tadashi Okabe
Keiko Takahashi
Nara Issei
Shinichi Hamaoka
Ueda Norihiro
Toshiaki Wakabayashi
Yasuhiro Funabashi
Taro Senba
Naoko Hata
Hiroyuki Yamamoto
Yoichi Ozawa
Naoko Tsukahara
Takashi Yamato
Application Number:
JP2001549363A
Publication Date:
March 04, 2009
Filing Date:
December 27, 2000
Export Citation:
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Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07D215/38; A61K31/352; A61K31/4375; A61K31/47; A61K31/4709; A61K31/472; A61K31/4725; A61K31/501; A61P3/10; A61P9/00; A61P9/10; A61P19/02; A61P29/00; A61P35/00; A61P35/02; A61P43/00; C07D215/48; C07D217/02; C07D217/22; C07D217/24; C07D217/26; C07D311/16; C07D311/18; C07D401/12; C07D405/12; C07D409/12; C07D411/12; C07D417/12; C07D471/04
Domestic Patent References:
JP3150560A
JP7267936A
JP5221997A
Other References:
Bioorg. Med. Chem.,1995年,Vol.3, No.2,p.129-141
J. Chem. Soc. C,1971年,No.22,p.3769-3778
Liebigs Ann. Chem.,1967年,Vol.707,p.242-249
Ann. Chim. (Rome),1963年,Vol.53,p.1850-1859
Chemical Abstracts,1946年,Vol.40,CA抄録番号40:10039,& Journal of the Chemical Society, 1945, p.867-870
Chemical Abstracts,1946年,Vol.40,CA抄録番号40:9973,& Zhurnal Obshchei Khimii, 1944, Vol.14, p.857-864
Attorney, Agent or Firm:
Satoshi Furuya
Takahiko Mizobe
Shinji Mochida
Yoshitsune Kazumasa