SULFONATED OLIGOSACCHARIDE COMPOUND AND ITS INTERMEDIATE - Director, AIST, Ministry of Economy, Trade and Industry

Title:

SULFONATED OLIGOSACCHARIDE COMPOUND AND ITS INTERMEDIATE

Document Type and Number:

Japanese Patent JP3163359

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To obtain a new sulfonated oligosaccharide compound having an amphipathic property and useful as a biological surfactant, its synthetic intermediate or the like.
SOLUTION: A compound of formula I [R10, R11 and R16 are each H, an acyl or a silyl; R12, R13 and R15 are each H or an acyl; R14 is H or an acyl which can easily be deacylated; R11 and R12, and R14 and R15 are each bounded to each other to form a (hemi)acetal; and Y is benzyloxy, hydroxyl group, a halogen or the like] or formula II [(n) is 1-3; R17 to R21 are each H, an acyl, benzyl or a silyl; R22 and R23 are each H, an acyl, a silyl or SO3M (M is H or an alkali metal); either of R22 and R23 is SO3M; and Y is benzyloxy, nitrophenoxy or the like]. The galactose compound of formula I is an intermediate for synthesizing the sulfated oligosaccharide compound of formula II. The compound of formula II is obtained by preparing a compound of formula IV (R1, R2 and R5 are each an acyl; and R4 is H or an acyl) from a compound of formula III as a starting raw material, and then reacting the prepared compound of formula IV with a sulfonating reagent.

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Inventors:

Hirotaka Uzawa
Taiichi Usui

Application Number:

JP35395099A

Publication Date:

May 08, 2001

Filing Date:

November 20, 1997

Export Citation:

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Assignee:

Director, AIST, Ministry of Economy, Trade and Industry

International Classes:

C07H11/00; A61K31/7024; A61K31/7028; A61K31/7034; A61P29/00; C07H15/04; C07H15/10; C07H15/14; C07H15/18; C07H15/203; C08B37/00; C08L101/16; C11D1/68; (IPC1-7): C07H11/00; C07H15/04; C08B37/00

Domestic Patent References:

JP423802A

Other References:

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