Title:
Sulfuration or sulfone oxidation many sugar of un-anti-coagulability
Document Type and Number:
Japanese Patent JP6228137
Kind Code:
B2
Abstract:
The present invention provides non-anticoagulant sulfated or sulfonated polysaccharides (NASPs), which accelerate the blood clotting process. Also provided are pharmaceutical formulations comprising a NASP of the invention in conjunction with a pharmaceutically acceptable excipient and, in various embodiments, these formulations are unit dosage formulations. The invention provides a NASP formulation, which is orally bioavailable. Also provided are methods for utilizing the compounds and formulations of the invention to promote blood clotting in vivo as therapeutic and prophylactic agents and in vitro as an aid to studies of the blood clotting process.
Inventors:
Doccal, Michael
Shaiflinger, Fritz
Knappe, Sabine
Till, Zuzane
High ton
Sanders, paul
Dande, Prasad
Jean, Con
Shaiflinger, Fritz
Knappe, Sabine
Till, Zuzane
High ton
Sanders, paul
Dande, Prasad
Jean, Con
Application Number:
JP2014554968A
Publication Date:
November 08, 2017
Filing Date:
January 30, 2013
Export Citation:
Assignee:
Bax Alta Game Behr
Bax Alta Incorporated
Bax Alta Incorporated
International Classes:
A61K31/737; A61K31/7024; A61K38/36; A61K38/37; A61P7/04; A61P43/00; G01N33/86
Domestic Patent References:
| JP61197601A | ||||
| JP2011116776A | ||||
| JP2012500780A | ||||
| JP2008500367A | ||||
| JP61155329A | ||||
| JP60036505A | ||||
| JP2001514630A | ||||
| JP9503510A |
Foreign References:
| WO2010031876A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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