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Title:
SUSTAINED RELEASE PREPARATION OF BEZAFIBRATE
Document Type and Number:
Japanese Patent JPH10167962
Kind Code:
A
Abstract:

To provide a sustained release tablet preparation containing bezafibrate with desirably prescribed persistency through simple manufacturing techniques.

This bezafibrate sustained release preparation is obtained by wet-granulating 1 pt.wt. of bezafibrate, 0.10-0.15 pt.wt. of lactose, 0.01-0.07 pt.wt. of hydroxypropylmethyl cellulose 2208 with a degree of methoxy substitution of 19.0-24.0% and a degree of hydroxypropoxy substitution degree of 4.0-12.0% on the dry basis, and 0.01-0.07 pt.wt. of hydroxypropylmethylcellulose 2910 with a degree of methoxy substitution of 28.0-30.0% and a degree of hydroxypropoxy substitution degree of 7.0-12.0% on the dry basis, admixing 0.01-0.03 pts.wt. of magnesium stearate to the resultant granules and making them tablets.


Inventors:
NAKAJIMA YOSHINORI
Application Number:
JP34449296A
Publication Date:
June 23, 1998
Filing Date:
December 10, 1996
Export Citation:
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Assignee:
DAITO KK
International Classes:
A61K9/22; A61K31/195; A61K47/38; A61P3/06; A61P9/00; A61P9/10; (IPC1-7): A61K31/195; A61K9/22; A61K47/38
Attorney, Agent or Firm:
Kusama Attack