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Title:
SUSTAINED RELEASE SUPPRESSIVE AGENT FOR CEREBRAL VASOSPASM
Document Type and Number:
Japanese Patent JPH07267880
Kind Code:
A
Abstract:

PURPOSE: To obtain a sustained release suppressive agent for cerebral vasospasm, containing a suppressive substance for the cerebral vasospasm on a sustained release carrier, usable by the intracephalic embedding, capable of manifesting effects on a morbid state in which therapeutic effects cannot be expected by an intravenous administration, a drainage methods, etc., and excellent in persistence of pharmacodynamic effects.

CONSTITUTION: This sustained release suppressive agent for cerebral vasospasm usable by the intracephalic embedding is obtained by supporting (B) a suppressive agent for the cerebral vasospasm such as a calcitonin-related peptide or maxadilan on (A) a sustained release carrier containing a water-soluble polymer such as hydroxypropyl cellulose, fats and oils such as hardened oils or waxes and a fatty acid such as stearic acid. Furthermore, the suppressive agent is preferably a tablet type for arranging in the subarachnoid space and/or sulci on the cerebral surface.


Inventors:
YOSHIMOTO TAKASHI
FUKUSHIMA SHOJI
Application Number:
JP24670094A
Publication Date:
October 17, 1995
Filing Date:
September 16, 1994
Export Citation:
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Assignee:
SHISEIDO CO LTD
International Classes:
A61K9/00; A61K38/00; A61K38/23; A61K45/00; A61K47/30; A61P9/00; (IPC1-7): A61K47/30; A61K9/00; A61K38/00; A61K38/23; A61K45/00
Attorney, Agent or Firm:
Heiyoshi Odashima (1 person outside)