Title:
SYN-ISOMER OF 3,7-DISUBSTD.-3-CEPHEM-4-CARBOXYLIC ACIDS, AND THEIR PREVENTINGOR TREATING AGENTS CONTAINING THEIR SALTS AS ACTIVE CONSTITUENT AGAINSTDISEASES CAUSED BY BACTERIAL INFECTION
Document Type and Number:
Japanese Patent JPS5368796
Kind Code:
A
Abstract:
PURPOSE: Syn-isomer of 3,7-disubstd.-3-cephem-4-carboxylic acids of formula I [R1 is radical II (R5 is H, halogen, etc., R6 is OH, alkoxy, etc.), radical III (R7 is amino, protected amino, etc.), radical IV (R8 is alkyl; R9 is imino, etc.); R2 is aliphatic hydrocarbon radical; R3 is carboxy, etc.; R4 is methyl, acyloxymethyl, methyl, etc.] and their salts, e.g. 7-[2-methoxyimino-2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-(1-methyl-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid (synisomer).
Inventors:
TAKATANI TAKAO
MASUGI TAKESHI
TAKASUGI HISASHI
KAWACHI HIROMU
MASUGI TAKESHI
TAKASUGI HISASHI
KAWACHI HIROMU
Application Number:
JP8249077A
Publication Date:
June 19, 1978
Filing Date:
July 08, 1977
Export Citation:
Assignee:
FUJISAWA PHARMACEUTICAL CO
International Classes:
A01N37/50; A01N43/78; A61K31/545; A61K31/546; A61P31/04; C07C251/48; C07C251/60; C07D277/20; C07D277/38; C07D277/40; C07D277/46; C07D333/16; C07D501/06; C07D501/20; C07D501/22; C07D501/24; C07D501/32; C07D501/34; C07D501/36; (IPC1-7): A61K31/545; C07D501/22; C07D501/32; C07D501/34; C07D501/36