抗菌剤と組み合わせた中極性油の細菌性バイオフィルムに対する相乗的抗菌活性

Japanese Patent JP6987039

B2

The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.

WO/2023/012810	METHOD AND SYSTEM FOR PRODUCTION OF ANTIMICROBIAL DISINFECTANT COATINGS USING ELECTROCHEMICAL SYNTHESIS
JP2010505887	Materials, items and products containing antimicrobial compositions
JP3169621	[Title of Invention] Antibacterial external preparation

Alexa Jovanovich
XIE Lei
Eric Roche
Paul Renick

JP2018510413A

December 22, 2021

August 23, 2016

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Smith & Nephew,Inc.

A61K33/38; A61K9/06; A61K9/08; A61K9/10; A61K9/107; A61K9/12; A61K31/23; A61L17/00; A61L27/30; A61L27/54; A61L29/02; A61L29/10; A61L29/16; A61L31/02; A61L31/08; A61L31/16; A61P17/00; A61P17/02; A61P31/04; A61P43/00

JP2013245187A
JP2006514944A
JP2012056854A

WO2011035158A2

日本形成外科学会基礎学術集会抄録,2013年,Vol.22,p.85, O-2
Antibacterial Synergy of Glycerol Monolaurate and Aminoglycosides in Staphylococcus aureus Biofilms,Antimicrobial Agents and Chemotherapy,2014年,58 (11),6970-6973
Assessment of cadexomer iodine against Staphylococcus aureus biofilm in vivo and in vivo using confocal laser scanning microscopy,Journal of Dermatology,2004年,31 (7),529-534
Antimicrobial Agents Chemotherapy,2014年,Vol.58, No.8,p.4353-4361
Int Wound J,2014年,Vol.11, No.6,p.730-734

Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe

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