Title:
核酸および／または他の構成要素を含有している合成ナノ構造体
Document Type and Number:
Japanese Patent JP5863670
Kind Code:
B2
Abstract:
Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanostructure core may be surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent.
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Inventors:
Saxton, Shad Sea.
Milkin, Chad A.
McMahon, Keirin
Tripathic, Shunt
Musarasan, Rajakanan
Leander, David M.
Lucy, Andrea
Milkin, Chad A.
McMahon, Keirin
Tripathic, Shunt
Musarasan, Rajakanan
Leander, David M.
Lucy, Andrea
Application Number:
JP2012549160A
Publication Date:
February 17, 2016
Filing Date:
January 19, 2011
Export Citation:
Assignee:
Northwestern University
International Classes:
A61K31/7088; A61K9/127; A61K9/51; A61K47/02; A61K47/42; A61K48/00; A61P3/06; A61P35/00
Foreign References:
| WO2009051451A1 | ||||
| WO2009131704A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto