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Title:
SYSTEM LEVEL CALIBRATION
Document Type and Number:
Japanese Patent JP2022119771
Kind Code:
A
Abstract:
To provide systems and methods of calibrating a microscope or an imaging system prior to acquiring image data of a sample.SOLUTION: A method includes the steps of: (a) running a power output calibration module to calibrate an imaging apparatus for repeatability (30); (b) running an image intensity calibration module to calibrate the imaging apparatus for reproducibility and to mitigate differences in detection efficiency between channels (31); (c) collecting image data from a microscope or an imaging system (32); (d) optionally running an unmixing module to unmix the collected image data into individual image channel images (33); and (e) optionally running a contrast agent intensity correction module to calibrate for differences in brightness between different contrast agents.SELECTED DRAWING: Figure 3

Inventors:
KARL ERIC GARSHA
DUSTIN KARL HARSHMAN
Application Number:
JP2022074031A
Publication Date:
August 17, 2022
Filing Date:
April 28, 2022
Export Citation:
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Assignee:
VENTANA MEDICAL SYSTEMS INC
International Classes:
G01N21/64; G01N21/27; G02B21/00
Domestic Patent References:
JP2012503180A2012-02-02
JP2016515203A2016-05-26
JP2015011127A2015-01-19
JP2013024906A2013-02-04
JP2016512345A2016-04-25
JP2004205508A2004-07-22
JP2011085587A2011-04-28
JP2008541179A2008-11-20
JP2014142657A2014-08-07
JP2012052985A2012-03-15
JP2004163312A2004-06-10
Foreign References:
WO2016087589A12016-06-09
WO2007097170A12007-08-30
WO2011104858A12011-09-01
US5880473A1999-03-09
Attorney, Agent or Firm:
Sonoda & Kobayashi Patent Attorneys Corporation