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Title:
T細胞受容体及びその使用
Document Type and Number:
Japanese Patent JP6989138
Kind Code:
B2
Abstract:
The present invention relates to the field of biotechnology. Specifically, the invention provides antigen-specific T-cell receptors (TCRs). Further, the invention encompasses polynucleotides encoding the same and vectors comprising said polynucleotides. Host cells comprising the molecules of the invention are also provided. Moreover, the invention provides means and methods for diagnostics and therapy, in particular of cancer.

Inventors:
Ellinger, Christian
Weener, Carina
Weiss, Manon
Wilde, Suzanne
Dolores, Shandel
Application Number:
JP2018565885A
Publication Date:
January 05, 2022
Filing Date:
June 16, 2017
Export Citation:
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Assignee:
Medigene Immunotherapy GAME BAHA
International Classes:
C12N15/12; A61K35/12; A61K38/17; A61K39/395; A61K47/64; A61K47/68; A61K48/00; A61P35/00; C07K14/725; C07K16/28; C07K19/00; C12N5/10; C12N15/63; C12P21/02; C12Q1/02; G01N33/574
Other References:
KESSLER J H,THE JOURNAL OF EXPERIMENTAL MEDICINE,米国,ROCKEFELLER UNIVERSITY PRESS,2001年,VOL:193, NR:1,PAGE(S):73 - 88,http://jem.rupress.org/content/jem/193/1/73.full.pdf,IN THE WIDELY EXPRESSED TUMOR ANTIGEN PRAME BY PROTEASOME-MEDIATED DIGESTION ANALYSIS
Attorney, Agent or Firm:
Patent business corporation Tsukuni