Title:
T1R3 NEW TASTE RECEPTOR
Document Type and Number:
Japanese Patent JP2010115201
Kind Code:
A
Abstract:
To provide the discovery, identification and characterization of a T1R3 receptor protein, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste.
There are provided T1R3 nucleotides, host cell expression systems, T1R3 proteins, fusion proteins, T1R3-transduced transgenic animals, and T1R3 "knock-out" animals. Further, there are provided methods for identifying modulators of the T1R3-mediated taste response, and the use of the modulators inhibiting or promoting the perception of bitterness or sweetness as flavor in foods, beverages and pharmaceuticals, are provided.
Inventors:
MARGOLSKEE ROBERT F
MAX MARIANNA
WEINSTEIN HAREL
CAMPAGNE FABIEN
SHANKER GOPI Y
MAX MARIANNA
WEINSTEIN HAREL
CAMPAGNE FABIEN
SHANKER GOPI Y
Application Number:
JP2009280365A
Publication Date:
May 27, 2010
Filing Date:
December 10, 2009
Export Citation:
Assignee:
SINAI SCHOOL MEDICINE
International Classes:
C12Q1/02; G01N33/68; A61K45/00; A61P25/02; C07K14/705; C07K14/72; C07K16/28; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; A61K38/00
Domestic Patent References:
| JP2004513608A | 2004-05-13 | |||
| JP2003531614A | 2003-10-28 |
Attorney, Agent or Firm:
Toru Sakamoto
Takuji Harada
Takuji Harada
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