Title:
TREATMENT WITH OPIOID ANTAGONISTS AND mTOR INHIBITORS
Document Type and Number:
Japanese Patent JP2015044847
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide cancer treatment with concomitant drugs.SOLUTION: The invention provides methods of treating a disorder or disease characterized by vascular endothelial cell growth factor-induced endothelial cell migration and proliferation by co-administering a synergistically effective amount of an mTOR inhibitor and a μ-opioid receptor antagonist.
Inventors:
MOSS JONATHAN
SINGLETON PATRICK A
SINGLETON PATRICK A
Application Number:
JP2014226368A
Publication Date:
March 12, 2015
Filing Date:
November 06, 2014
Export Citation:
Assignee:
UNIV CHICAGO
International Classes:
A61K45/06; A61K31/436; A61K31/485; A61P3/10; A61P5/14; A61P7/06; A61P9/00; A61P17/00; A61P19/02; A61P21/00; A61P25/00; A61P27/02; A61P29/00; A61P35/00; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| JP2007523188A | 2007-08-16 | |||
| JP2007505939A | 2007-03-15 |
Foreign References:
| WO2007121447A2 | 2007-10-25 | |||
| WO2006096626A2 | 2006-09-14 | |||
| WO2006125540A1 | 2006-11-30 | |||
| WO2007124252A2 | 2007-11-01 | |||
| WO2007131689A2 | 2007-11-22 |
Other References:
JPN6013044198; ファルマシア Ｖｏｌ．４２， Ｎｏ．２, 2006, ｐ．１７３-１７４
Attorney, Agent or Firm:
Mutsumi Sameshima
Yasuo Tamura
Hisatoshi Shinagawa
Yasushi Morimoto
Yasuo Tamura
Hisatoshi Shinagawa
Yasushi Morimoto