Title:
HIVウイルスの指向性を予測するための技術およびアミノ酸配列を分類するための技術
Document Type and Number:
Japanese Patent JP2012506099
Kind Code:
A
Abstract:
Techniques for categorizing a test sequence are disclosed. An exemplary technique includes defining and utilizing Position Specific Score Matrices that takes into account dependencies of adjacent positions. An embodiment includes predicting HIV viral tropism with improved specificity and sensitivity. Another embodiment includes subdividing a training data set into a set of data subsets, training a plurality of classifiers based on the data subsets, and taking a vote of the plurality of classifiers. Yet another embodiment relates to weighting, in creating a training set, a specified data point based on a distance from the specified data point to an average of the reference plurality of data points.
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Inventors:
Liao, Guo Chun
Jung, Min
Jung, Min
Application Number:
JP2011532258A
Publication Date:
March 08, 2012
Filing Date:
October 15, 2009
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
G16B40/00; C12Q1/68; G01N33/48; G01N33/50; G01N33/68; G16B30/00
Attorney, Agent or Firm:
Fukami patent office