Title:
TETRACYCLINE DERIVATIVES FOR TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS
Document Type and Number:
Japanese Patent JP2018039846
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide tetracycline derivatives for treatment of bacterial, viral and parasitic infections.SOLUTION: The present invention pertains, at least in part, to substituted tetracycline compounds of the formula (I), where X is CHC(RY'Y), CRR, C=CRR, S, NR, or O; E is NRR, OR, or (CH)C(=W')WR; W is O, S, NR, or CRR; and W' is O, S, or NR. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms.SELECTED DRAWING: None
Inventors:
ABATO PAUL
ASSEFA HAREGEWEIN
BERNIAC JOEL
BHATIA BEENA
BOWSER TODD
GRIER MARK
HONEYMAN LAURA
ISMAIL MOHAMED
KIM OAK K
NELSON MARK
PAN JINGWEN
VERMA ATUL
ASSEFA HAREGEWEIN
BERNIAC JOEL
BHATIA BEENA
BOWSER TODD
GRIER MARK
HONEYMAN LAURA
ISMAIL MOHAMED
KIM OAK K
NELSON MARK
PAN JINGWEN
VERMA ATUL
Application Number:
JP2017238683A
Publication Date:
March 15, 2018
Filing Date:
December 13, 2017
Export Citation:
Assignee:
PARATEK PHARM INNC
International Classes:
C07C237/26; A61K31/65; A61P17/00; A61P17/10; A61P25/28; A61P29/00; A61P31/04; A61P33/06; C07C235/40; C07C239/20; C07C251/34; C07C251/52; C07C255/59; C07D207/337; C07D207/50; C07D213/56; C07D231/12; C07D241/12; C07D261/04; C07D261/08; C07D263/32; C07D307/54; C07D309/22
Domestic Patent References:
| JP2004502753A | 2004-01-29 | |||
| JP2005514410A | 2005-05-19 | |||
| JP2006503898A | 2006-02-02 |
Foreign References:
| WO2004064728A2 | 2004-08-05 | |||
| WO2005009943A2 | 2005-02-03 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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