Title:
ヒスタミンH3受容体アンタゴニストとしてのテトラヒドロナフチリジンおよびそれらのアザ誘導体
Document Type and Number:
Japanese Patent JP2011518127
Kind Code:
A
Abstract:
The invention relates to compounds of formula (I), wherein X1a, X1 to X5, Ra, Rb, n and R have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.
Inventors:
Adam James Davenport
David James Hallett
Frederick Merlin
Marc Gemkov
David James Hallett
Frederick Merlin
Marc Gemkov
Application Number:
JP2011502355A
Publication Date:
June 23, 2011
Filing Date:
March 27, 2009
Export Citation:
Assignee:
Evotech Actien Gezel Shaft
International Classes:
C07D471/04; A61K31/4375; A61K31/4545; A61K31/519; A61K31/5377; A61P1/00; A61P3/00; A61P9/00; A61P11/02; A61P11/06; A61P25/00; A61P29/00; A61P37/08; A61P43/00; C07D471/14; A61P3/04; A61P3/10; A61P9/10; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; C07B61/00
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi
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