Title:
テトラゾロン置換ステロイド及びその使用
Document Type and Number:
Japanese Patent JP7340023
Kind Code:
B2
Abstract:
The present disclosure relates to compounds of formula (AI), (I), (AII), and (II), or a pharmaceutically acceptable salt, solvate, stereoisomer, or tautomer thereof, a pharmaceutical composition comprising a compound of formula (AI), (I), (AII), and (II), and use thereof, wherein R2, R3, R4, R5, R6, R7, R10, R11a, R11b, R12, R16, R19a, R19b, and R20 are described herein. Such compounds are envisioned useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, movement disorders, convulsive disorders, schizophrenin spectrum disorders, disorders of memory and/or cognition, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, or tinnitus etc.
Inventors:
Lee, Hui
Song, Yung Tao
Song, Yung Tao
Application Number:
JP2021537711A
Publication Date:
September 06, 2023
Filing Date:
January 14, 2020
Export Citation:
Assignee:
Beijing Shuen Yi Pharma Sciences Company, Limited
International Classes:
C07J43/00; A61K31/58; A61K45/00; A61P9/00; A61P23/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/18; A61P25/20; A61P25/22; A61P25/28; A61P25/30; A61P27/16; A61P43/00
Domestic Patent References:
| JP6329695A | ||||
| JP2019520417A | ||||
| JP2018502890A |
Foreign References:
| WO1998005337A1 |
Other References:
BROWN, H.D. et al.,J.Med.Chem.,1963年,6,795-796
CRABBE, Pierre et al.,J.Org.Chem.,1973年,38(8),1478-1483
CRABBE, Pierre et al.,J.Org.Chem.,1973年,38(8),1478-1483
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito