Title:
TG SYNTHESIS INHIBITOR
Document Type and Number:
Japanese Patent JP2010070541
Kind Code:
A
Abstract:
To provide a TG synthesis inhibitor effective for prevention or amelioration of hyperlipidemia and obesity.
The TG synthesis inhibitor comprises as an effective ingredient thereof ellagitannin, having a partial structure represented by formula (1) and a glucose residue in the molecule and having the 4- and 6-positions of the glucose residue substituted with a hexahydroxydiphenoyl group portion in the partial structure represented by formula (1), or a derivative thereof.
Inventors:
KONDO HIDEHIKO
HASHIZUME KOJIRO
MURASE TAKATOSHI
HASHIZUME KOJIRO
MURASE TAKATOSHI
Application Number:
JP2009183643A
Publication Date:
April 02, 2010
Filing Date:
August 06, 2009
Export Citation:
Assignee:
KAO CORP
International Classes:
A61K31/7024; A61P3/04; A61P3/06; A61P3/10; C07H9/02
Domestic Patent References:
| JPH09176019A | 1997-07-08 | |||
| JP2008184383A | 2008-08-14 | |||
| JP2006056850A | 2006-03-02 | |||
| JP2008280291A | 2008-11-20 | |||
| JPH09176019A | 1997-07-08 | |||
| JP2008184383A | 2008-08-14 | |||
| JP2006056850A | 2006-03-02 | |||
| JP2008280291A | 2008-11-20 | |||
| JP2010070540A | 2010-04-02 |
Other References:
JPN6013054799; Ｈａｔｔｏｒｉ，Ｋ． ｅｔ ａｌ．: Ｊｏｕｒｎａｌ ｏｆ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｃｉｅｎｃｅｓ Ｖｏｌ．９３， Ｎｏ．１, 2003, ｐ．６９-７３
JPN6013054801; Ｆｕｋｕｄａ，Ｔ． ｅｔ ａｌ．: ＢｉｏＦａｃｔｏｒｓ Ｖｏｌ．２１， Ｎｏ．１-４, 2004, ｐ．２５１-３
JPN6013054803; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３４-４２３７
JPN6013054805; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３０-４２３３
JPN6013054806; Ａｇａｔａ，Ｉ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３９， Ｎｏ．４, 1991, ｐ．８８１-８８３
JPN6013054799; Ｈａｔｔｏｒｉ，Ｋ． ｅｔ ａｌ．: Ｊｏｕｒｎａｌ ｏｆ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｃｉｅｎｃｅｓ Ｖｏｌ．９３， Ｎｏ．１, 2003, ｐ．６９-７３
JPN6013054801; Ｆｕｋｕｄａ，Ｔ． ｅｔ ａｌ．: ＢｉｏＦａｃｔｏｒｓ Ｖｏｌ．２１， Ｎｏ．１-４, 2004, ｐ．２５１-３
JPN6013054803; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３４-４２３７
JPN6013054805; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３０-４２３３
JPN6013054806; Ａｇａｔａ，Ｉ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３９， Ｎｏ．４, 1991, ｐ．８８１-８８３
JPN6013054801; Ｆｕｋｕｄａ，Ｔ． ｅｔ ａｌ．: ＢｉｏＦａｃｔｏｒｓ Ｖｏｌ．２１， Ｎｏ．１-４, 2004, ｐ．２５１-３
JPN6013054803; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３４-４２３７
JPN6013054805; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３０-４２３３
JPN6013054806; Ａｇａｔａ，Ｉ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３９， Ｎｏ．４, 1991, ｐ．８８１-８８３
JPN6013054799; Ｈａｔｔｏｒｉ，Ｋ． ｅｔ ａｌ．: Ｊｏｕｒｎａｌ ｏｆ ｐｈａｒｍａｃｏｌｏｇｉｃａｌ ｓｃｉｅｎｃｅｓ Ｖｏｌ．９３， Ｎｏ．１, 2003, ｐ．６９-７３
JPN6013054801; Ｆｕｋｕｄａ，Ｔ． ｅｔ ａｌ．: ＢｉｏＦａｃｔｏｒｓ Ｖｏｌ．２１， Ｎｏ．１-４, 2004, ｐ．２５１-３
JPN6013054803; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３４-４２３７
JPN6013054805; Ｏｋｕｄａ，Ｔ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３０， Ｎｏ．１１, 1982, ｐ．４２３０-４２３３
JPN6013054806; Ａｇａｔａ，Ｉ． ｅｔ ａｌ．: Ｃｈｅｍｉｃａｌ ａｎｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ Ｖｏｌ．３９， Ｎｏ．４, 1991, ｐ．８８１-８８３
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
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