PURPOSE: To obtain the subject therapeutic agent, containing leucovorin as an active ingredient and capable of manifesting the reducing actions on the yellowness as an internal treatment in place of the surgical percutaneous transhepatic biliary tract drainage(PTBD) treatment.
CONSTITUTION: This therapeutic agent for obstructive jaundice contains leucovorin as an active ingredient. The therapeutic agent is orally (parenterally) and locally administered together with an excipient such as starch, lactose, white sugar, crystalline cellulose or calcium hydrogenphosphate, a binder such as acacia, hydroxypropyl cellulose, alginic acid, gelatin or polyvinylpyrrolidone, a lubricant such as stearic acid (magnesium stearate), calcium stearate, tale or a hydrogenated vegetable oil, a disintegrating agent such as a modified starch calcium carboxymethyl cellulose, a dissolving adjuvant such as a nonionic surfactant or an anionic surfactant.
LEDERLE JAPAN LTD
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