PURPOSE: To obtain a therapeutic agent for osteoporosis containing bark of Eucommia ulmoides oliv. or root of Astragalus membranaceus Burge and being free from side effects and extremely effective.

CONSTITUTION: The objective agent containing powder of bark of Eucommia ulmoides oliv. which has been used for depression of blood pressure or urination or powder of root of Astragalus membranaceus Burge which has been used for depression of blood pressure, urination or tonic or 50% methanol extract thereof. The powder or extract may be directly orally used or may be used in a form of an oral medicine composition combined with one or more kinds of pharmaceutically acceptable medicine auxiliary agents in common use. Dose of the agent is preferably normally 0.5-5g/adult day as powder and 0.2-2g/adult day as extract.