Title:
治療用アポトーシス細胞調製物、その製造方法及びその使用
Document Type and Number:
Japanese Patent JP6722261
Kind Code:
B2
Abstract:
The present application provides pharmaceutical compositions comprising a population of mononuclear-enriched cells in an early-apoptotic state, methods for the production of said compositions and uses thereof in the treatment of diseases characterized by pathological immune responses. The pharmaceutical compositions may be used in treatment of conditions such as, but not limited to, graft versus host disease (GVHD) and autoimmune diseases including but not limited to inflammatory bowel disease, gout and arthritis.
Inventors:
Mevolak, Droll
Rainier, Inna
Rainier, Inna
Application Number:
JP2018219334A
Publication Date:
July 15, 2020
Filing Date:
November 22, 2018
Export Citation:
Assignee:
Enrivex Therapeutics Limited
International Classes:
C12N5/078; A61K35/17; C12N5/0781; C12N5/0783; C12N5/0786
Domestic Patent References:
| JP2005517637A | ||||
| JP2012512843A | ||||
| JP2008540400A | ||||
| JP2012524795A | ||||
| JP2005187472A | ||||
| JP2007326824A | ||||
| JP2009178129A | ||||
| JP2006507271A | ||||
| JP2012077006A | ||||
| JP2005528319A | ||||
| JP2003527442A | ||||
| JP2002179579A |
Foreign References:
| WO2009001545A1 | ||||
| WO2012141032A1 | ||||
| US7544355 |
Other References:
Bone Marrow Transplantation (2011) Vol.46, Suppl.1, pp.S312-S313, P1024
Blood (2001) Vol.98, pp.224-230
Ann. N.Y. Acad. Sci. (2010) Vol.1209, pp.118-126
Blood (2001) Vol.98, pp.224-230
Ann. N.Y. Acad. Sci. (2010) Vol.1209, pp.118-126
Attorney, Agent or Firm:
Patent business corporation Oshima patent office