Title:
Therapeutic combined use of DLL4 antagonist and a hypotensor, and the method of the medical treatment by them
Document Type and Number:
Japanese Patent JP5965318
Kind Code:
B2
Abstract:
Methods for treating cancer comprising administering a DLL4 antagonist and one or more anti-hypertensive agents are described. Also described are pharmaceutical compositions comprising a DLL4 antagonist and one or more anti-hypertensive agents, and kits comprising the same.
Inventors:
Stag robert joseph
Benner Stephen Eugene
Benner Stephen Eugene
Application Number:
JP2012534438A
Publication Date:
August 03, 2016
Filing Date:
October 18, 2010
Export Citation:
Assignee:
Oncomed Pharmaceuticals Incorporated
International Classes:
A61K39/395; A61K31/165; A61K31/365; A61K31/41; A61K31/4164; A61K31/4178; A61K31/4184; A61K45/00; A61K45/06; A61P9/12; A61P35/00; A61P35/02; A61P43/00
Foreign References:
| WO2008042236A1 | ||||
| WO2007143689A1 |
Other References:
Timothy Hoey et al,Cell Stem Cell,2009年 8月 7日,vol.5, no.2,p.168-177
Andrew S. Chi et al,The Oncologist,2009年 6月,vol.14, no.6,p.621-636
Herbert I. Hurwitz et al ,Clinical Cancer Research,2009年 6月15日,vol.15, no.12,p.4220-4227
Andrew S. Chi et al,The Oncologist,2009年 6月,vol.14, no.6,p.621-636
Herbert I. Hurwitz et al ,Clinical Cancer Research,2009年 6月15日,vol.15, no.12,p.4220-4227
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
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